Decoding and Encoding of Molecular Information in Distributed Cellular Systems
Speaker: Madan Rao (NCBS, Bangalore, India)
Date: 20/04/2023
Time: 10:30
If you would like to attend the seminar, please registe here
It is often useful to think about Cells and Tissues as Distributed Computing Systems, especially in the context of the processing of noisy molecular information. I will illustrate this in two parts. In the first, I will talk about cellular compartmentalisation and receptor promiscuity as a strategy for accurate inference of position during Morphogenesis. In the second, I will discuss the synthesis of a complex Glycan code in the Golgi cisternae, and how cisternal number and enzyme promiscuity achieves the target distribution with high fidelity.